Investigation of gliadin binding to different selected proteins using a biotin-streptavidin system (1) Binding of gliadins to constituents of the coeliac patients’ mucosa may represent…
Science
Diagnostic accuracy of a new point-of-care screening assay for celiac disease
Diagnostic accuracy of a new point-of-care screening assay for celiac disease(1) The initial diagnosis of CD is made by serological testing and confirmed either by…
The intestine–renal connection in IgA nephropathy
The intestine–renal connection in IgA nephropathy (1) The mucosal surfaces of respiratory and gastrointestinal tracts represent a 400 m2 interface with the environment constituted by…
In vitro presentation of gliadin-derived peptides by different cell lines
In vitro presentation of gliadin-derived peptides by different cell lines (1) The amount and complexity of dietary antigens and microorganisms that challenge the surface of…
Microfluorimeter with disposable polymer chip for detection of coeliac disease toxic gliadin
Microfluorimeter with disposable polymer chip for detection of coeliac disease toxic gliadin (1) Coeliac disease is not an allergy; it is an auto-immune disease, which…
Immunological Significance of HMGB1 Post-Translational Modification and Redox Biology
Immunological Significance of HMGB1 Post-Translational Modification and Redox Biology (1) The human HMGB1 protein has 215 amino acid (aa) residues (MW: 25–30 kDa) that form…
High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule
High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule (1) The detection of extracellular HMGB1 as a delayed mediator after LPS stimulation….
The need for IgG2c specific antiserum when isotyping antibodies from C57BLr6 and NOD mice
The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice (1) In mice, antibodies of the IgG2a, subclass are the predominant…
Possible allelic structure of IgG2a and IgG2c in mice
Possible allelic structure of IgG2a and IgG2c in mice (1) Igh-1a and Igh-1b could derive from two distinct isotypes, IgG2a and IgG2c, which are organized…
A mouse model for food allergy using intraperitoneal sensitization
A mouse model for food allergy using intraperitoneal sensitization(1) There exists a correlation between the relative resistance of a protein to digestion by pepsin in…
Modulation of the immune response by probiotic strains in a mouse model of gluten sensitivity
Modulation of the immune response by probiotic strains in a mouse model of gluten sensitivity (1) Bacteria associated with probiotic activity have frequently been lactic…
A novel and sensitive method for the detection of T cell stimulatory epitopes of a/b- and g-gliadin
A novel and sensitive method for the detection of T cell stimulatory epitopes of a/b- and g-gliadin (1) CD is an immune disease caused by…
Important Lessons Derived from Animal Models of Celiac Disease
Important Lessons Derived from Animal Models of Celiac Disease (1) Rats Germ free Wistar AVN rats were used to study the effects of administering gliadin…
HYDROPHOBIC INTERACTIONS BETWEEN GLIADIN AND PROTEINS AND CELIAC DISEASE
HYDROPHOBIC INTERACTIONS BETWEEN GLIADIN AND PROTEINS AND CELIAC DISEASE (1) Celiac disease(CD) is characterized by damage of the small intestinal mucosa developed by the presence…
Development of high‐sensitive enzyme immunoassays for gliadin quantification using the streptavidin‐biotin amplification system
Development of high‐sensitive enzyme immunoassays for gliadin quantification using the streptavidin‐biotin amplification system (1) Coeliac disease (CD) occurs in genetically susceptible individuals as a result…
Affinity of aptamers binding 33-mer gliadin peptide and gluten proteins: Influence of immobilization and labeling tags
Affinity of aptamers binding 33-mer gliadin peptide and gluten proteins: Influence of immobilization and labeling tags (1) The high affinity of aptamers for their cognate…
Latest In vitro and in vivo models of celiac disease
Latest In vitro and in vivo models of celiac disease (1) Ingestion of wheat-derived gluten by celiac patients results in immune mediated injury of the…
Gluten Ataxia – Passive Transfer in a Mouse Model
Gluten Ataxia – Passive Transfer in a Mouse Model (1) Celiac disease [CD] is accompanied by the production of anti- gliadin (AGA) and anti-tissue transglutaminase…
Cross-reactivity between the major allergen from olive pollen and unrelated glycoproteins: Evidence of an epitope in the glycan moiety of the allergen
Cross-reactivity between the major allergen from olive pollen and unrelated glycoproteins: Evidence of an epitope in the glycan moiety of the allergen (1) The major…
Identification and cloning of a complementary DNA encoding a vicilin-like proprotein, Jug r 2, from English walnut kernel (Juglans regia), a major food allergen
Identification and cloning of a complementary DNA encoding a vicilin-like proprotein, Jug r 2, from English walnut kernel (Juglans regia), a major food allergen (1)…