Structural and functional characterization of the Curli adaptor protein CsgF(1) Untangling a Repetitive Amyloid Sequence: Correlating Biofilm‐Derived and Segmentally Labeled Curli Fimbriae by Solid‐State NMR…

Biodegradable zinc oxide composite scaffolds promote osteochondral differentiation of mesenchymal stem cells (1) Zinc is an essential nutrient for many physiological functions including growth, DNA…

T cell epitope mimicry between Sjögren’s syndrome Antigen A (SSA)/Ro60 and oral, gut, skin and vaginal bacteria (1) Cross-reactivity between Ro60 and EBV protein EBNA-1…

Arthropathic Properties Related to the Molecular Weight of Peptidoglycan-Polysaccharide Polymers of Streptococcal Cell Walls (1) The covalently bound polymers of peptidoglycan and group-specific polysaccharide (PG-APS)…

Does age matter? The impact of rodent age on study outcomes (1) The quality of data obtained from rodent models and these factors differ according…

Optimized extraction of glycosaminoglycans from normal and osteoarthritic cartilage for glycomics profiling (1) The functioning ability of cartilage is dependent on the maintenance of the…

Anti-Neutrophil Cytoplasmic Antibodies and Effector CD4 Cells Play Nonredundant Roles in Anti-Myeloperoxidase Crescentic Glomerulonephritis(1) MPO-ANCA–associated “pauci-immune” crescentic GN in humans therefore may be a three-step…

Extraction, Isolation and Analysis of Chondroitin Sulfate Glycosaminoglycans (1) Glycosaminoglycans (GAGs) are a straight chain anionic polysaccharide composed of repeating disaccharide units of hexosamine (glucosamine…

A semi-empirical method for prediction of antigenic determinants on protein antigens(1) Identification of epitopes on proteins would be useful for diagnostic purposes and also in…

Animal models of anti-neutrophil cytoplasmic antibody-associated vasculitis(1). Anti-neutrophil cytoplasmic antibody (ANCA) vasculitis is a severe systemic disease that affects joints, lungs, kidneys, skin and other…

Experimental Autoimmune Anti-MPO Disease Induced by Active Immunization With MPO (1) GN is triggered by injection of a low dose of sheep anti-mouse glomerular basement…

Toll-like Receptor 2 Induces Th17 Myeloperoxidase Autoimmunity While Toll-like Receptor 9 Drives Th1 Autoimmunity in Murine Vasculitis (1) When T-cells are activated, CD4 cells differentiate…

A new mouse model of anti-GBM disease sheds light on maternal transfer of alloantibodies in glomerular disease (1) In Membranous nephropathy (MN), the two main…

Passive Transfer of Anti-MPO Antibodies (1) Enhancement of glomerular injury caused by anti-glomerular basement membrane (GBM) antibodies when co-administered with anti-Myeloperoxidase (MPO) serum. Mouse models…

Large-Scale Purification of Myeloperoxidase from HL60 Promyelocytic Cells: Characterization and Comparison to Human Neutrophil Myeloperoxidase (1) Myeloperoxidase (MPO) is a heme-containing protein found in the…

Preparation and Extraction of Insoluble (Inclusion-Body) Proteins from Escherichia coli (1) High level expression of recombinant protein in E.coli leads to the formation of highly…

Thioether-Bonded Constructs of Fab′γ and Fc γ Modules Utilizing Differential Reduction of Interchain Disulfide Bonds (1) It is a benefit for therapeutics if we have…

A novel mouse model for MPO-ANCA-associated glomerulonephritis.(1) Animal models have been used for studying the mechanisms for the development of vasculitis. The SCG/Kj mouse is…

Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3 (1) A 29 kDa neutrophil serine proteinase was identified as an autoantigen of anti-neutrophil cytoplasmic autoantibodies (ANCA)…

Inflammation-associated enterotypes, hostgenotype, cage and inter-individual effectsdrive gut microbiota variation in commonlaboratory mice (1) Mouse disease models are crucial for gut microbiome research. Unfortunately, genetic…