Autoantibodies to BPAG1e trigger experimental bullous pemphigoid in mice (1) Bullous pemphigoid (BP) is the most common subepidermal autoimmune blistering disease characterized by autoantibodies in…
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Human IgG1 Monoclonal Antibody against Human Collagen 17 Noncollagenous 16A Domain Induces Blisters via Complement Activation in Experimental Bullous Pemphigoid Model
Human IgG1 Monoclonal Antibody against Human Collagen 17 Noncollagenous 16A Domain Induces Blisters via Complement Activation in Experimental Bullous Pemphigoid Model (1) Bullous pemphigoid (BP)…
Bullous Pemphigoid Autoantibodies Directly Induce Blister Formation without Complement Activation
Bullous Pemphigoid Autoantibodies Directly Induce Blister Formation without Complement Activation (1) Studies to map the epitopes on COL17 have revealed that the juxtamembranous extracellular noncollagenous…
Passive transfer of collagen XVII-specific antibodies induces sustained blistering disease in adult mice
Passive transfer of collagen XVII-specific antibodies induces sustained blistering disease in adult mice (1) Bullous pemphigoid (BP) is characterized by the presence of tissue-bound and…
Peanut protein concentrate: Production and functional properties as affected by processing
Peanut protein concentrate: Production and functional properties as affected by processing(1) Vegetable oil extraction from peanut yields partially defatted peanut flour (DPF). DPF is protein-rich,…
Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family
Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family (1) mTIM-1 is…
Processing Can Alter the Properties of Peanut Extract Preparations
Processing Can Alter the Properties of Peanut Extract Preparations (1) Several different enzyme-linked immunosorbent assay (ELISA) methods are being used to detect either the common…
Peanut protein extraction conditions strongly influence yield of allergens Ara h 1 and 2 and sensitivity of immunoassays
Peanut protein extraction conditions strongly influence yield of allergens Ara h 1 and 2 and sensitivity of immunoassays(1) Extraction is the basis for all subsequent…
Epicutaneous immunotherapy on intact skin using a new delivery system in a murine model of allergy
Epicutaneous immunotherapy on intact skin using a new delivery system in a murine model of allergy (1) Viaskin is a new epicutaneous delivery system (EDS)…
A tractable covalent linker strategy for the production of immunogenic antigen-TLR7/8L bioconjugates
A tractable alent linker strategy for the production of immunogenic antigen-TLR7/8L bioconjugates (1) Direct covalent attachment of Toll-like receptor (TLR) agonists to antigenic proteins has…
Blocking monoclonal antibodies of TIM proteins as orchestrators of anti-tumor immune response
Blocking monoclonal antibodies of TIM proteins as orchestrators of anti-tumor immune response (1) T cell immunoglobulin and mucin domain (TIM) proteins are type-I cell-surface molecules…
Effector Activity of Peanut Allergens: A critical role for Ara h 2, Ara h 6, and their variants
Effector Activity of Peanut Allergens: A critical role for Ara h 2, Ara h 6, and their variants(1). The term “major allergen” is defined as…
Identification of the major water/salt insoluble wheat proteins involved in cereal hypersensitivity
Identification of the major water/salt insoluble wheat proteins involved in cereal hypersensitivity (1) Bakers’ asthma is an occupational hypersensitivity disease primarily caused by the inhalation…
The conformation of wheat gluten proteins
The conformation of wheat gluten proteins. The secondary structures and thermal stabilities of α-, β-, γ- and ω-Gliadins (1) Wheat gluten is the visco-elastic mass…
Fast ω-gliadin is a major allergen in wheat-dependent exercise-induced anaphylaxis
Fast ω-gliadin is a major allergen in wheat-dependent exercise-induced anaphylaxis (1) An immediate-type hypersensitivity to water/salt-insoluble fraction of wheat proteins (gluten), has been considered to…
Structure of the Major Peanut Allergen Ara h 1 May Protect IgE-Binding Epitopes from Degradation
Structure of the Major Peanut Allergen Ara h 1 May Protect IgE-Binding Epitopes from Degradation (1) Peanuts are widely used for the preparation of a…
Engineering approaches for studying immune-tumor cell interactions and immunotherapy
Engineering approaches for studying immune-tumor cell interactions and immunotherapy (1) Cancer immunotherapy includes several methods to boost the immune system’s response to cancer such as…
Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2
Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2 (1) House dust mites have…
Evaluation of Reduced Allergenicity of Deamidated Gliadin in a Mouse Model of Wheat-Gliadin Allergy Using an Antibody Prepared by a Peptide Containing Three Epitopes
Evaluation of Reduced Allergenicity of Deamidated Gliadin in a Mouse Model of Wheat-Gliadin Allergy Using an Antibody Prepared by a Peptide Containing Three Epitopes (1)…
Digestion of peanut allergens Ara h 1, Ara h 2, Ara h 3, and Ara h 6: A comparative in vitro study and partial characterization of digestion-resistant peptides
Digestion of peanut allergens Ara h 1, Ara h 2, Ara h 3, and Ara h 6: A comparative in vitro study and partial characterization…