Sensitization and Elicitation of an Allergic Reaction to Wheat Gliadins in Mice (1) Wheat flour proteins are divided in albumins and globulins (AG) that are…
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Identification of Immunodominant Epitopes of -Gliadin in HLA-DQ8 Transgenic Mice following Oral Immunization
Identification of Immunodominant Epitopes of -Gliadin in HLA-DQ8 Transgenic Mice following Oral Immunization (1) A major feature of celiac disease is the inap- propriate intestinal…
Glomerular deposition of food antigens in IgA nephropathy
Glomerular deposition of food antigens in IgA nephropathy (1) The participation of some food antigens has been reported, and the mucosal immune system of the…
Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of
Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease (1) The tolerogenic potential of antigen loaded, negatively charged nanoparticles (referred to…
Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes
Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes (1) Until now, 12 allergens (Ara h 1 to Ara h…
Gluten and IgA nephropathy: you are what you eat
Gluten and IgA nephropathy: you are what you eat? (1) IgA derived from mesangial deposits is typically of the IgA1 isoform, polymeric, and poorly galactosylated…
LACK OF ORAL TOLERANCE IN C3H/HeJ MICE
LACK OF ORAL TOLERANCE IN C3H/HeJ MICE (1) Oral toleranceto solubleantigenhasalsobeenattributedto theinductionof T8cellsin thegut-associatedlymphoreticulartissue(GALT), e.g.,Peyer’spatches. High IgA immune responses to orally administered,thymic-dependent(TD) antigen occur in…
Immune Responses to Fed Protein Antigens in Mice
Immune Responses to Fed Protein Antigens in Mice. 3. Systemic Tolerance or Priming Is Related to Age at Which Antigen Is First Encountered.(1) Tolerance is…
IgE-mediated mechanisms in bullous pemphigoid and other autoimmune bullous diseases
IgE-mediated mechanisms in bullous pemphigoid and other autoimmune bullous diseases (1) Autoimmune bullous diseases (AIBDs) comprise a heterogeneous group of about a dozen entities that…
Epidermal aspects of type VII collagen: Implications for dystrophic epidermolysis bullosa and epidermolysis bullosa acquisita
Epidermal aspects of type VII collagen: Implications for dystrophic epidermolysis bullosa and epidermolysis bullosa acquisita (1) In 28 different types of collagen family, type VII…
The Autoantigen of Anti-p200 Pemphigoid Is an Acidic Noncollagenous N-Linked Glycoprotein of the Cutaneous Basement Membrane
The Autoantigen of Anti-p200 Pemphigoid Is an Acidic Noncollagenous N-Linked Glycoprotein of the Cutaneous Basement Membrane (1) Indirect immunofluorescence of pa- tients’ sera demonstrates circulating…
Molecular Mapping of the Major Epitopes of BP180 Recognized by Herpes Gestationis Autoantibodies
Molecular Mapping of the Major Epitopes of BP180 Recognized by Herpes Gestationis Autoantibodies (1) Herpes gestationis (HG) is a nonherpetic autoimmune disease of women characterized…
Minor collagens of the skin with not so minor functions
Minor collagens of the skin with not so minor functions (1) The skin is an essential chemical and physical barrier between our bodies and the…
Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen
Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen (1) Epidermolysis bullosa acquisita (EBA), a severe chronic subepidermal…
Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice (Marraccini et al
Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice (1) Characterized by rhinitis which often accompanies respiratory symptoms such as…
Antibodies to Pathogenic Epitopes on TypeXVII Collagen Cause Skin Fragility in a Complement-Dependent and -Independent Manner
Antibodies to Pathogenic Epitopes on TypeXVII Collagen Cause Skin Fragility in a Complement-Dependent and -Independent Manner (1) Type XVII collagen (COL17; formerly called BPAG2 or…
Sensitization to acid-hydrolyzed wheat protein by transdermal administration to BALB/c mice, and comparison with gluten
Sensitization to acid-hydrolyzed wheat protein by transdermal administration to BALB/c mice, and comparison with gluten.(1) Wheat-dependent exercise-induced anaphylaxis (WDEIA) is one of the most important…
Priming of systemic and local delayed-type hypersensitivity responses by feeding low doses of ovalbumin to mice
Priming of systemic and local delayed-type hypersensitivity responses by feeding low doses of ovalbumin to mice (1) When oral tolerance of systemic DTH responses can…
Antigen-specific gut inflammation and systemic immune responses induced by pro-longing wheat gluten sensitization in BALB/c murine model
Antigen-specific gut inflammation and systemic immune responses induced by pro-longing wheat gluten sensitization in BALB/c murine model (1) The wheat seed contains 80% of storage…
Wheat gliadin deamidated by cation-exchange resins induces oral tolerance in a mouse model of wheat allergy
Wheat gliadin deamidated by cation-exchange resins induces oral tolerance in a mouse model of wheat allergy (1) The currently understood mechanism of the oral-SIT is…