Pemphigus Vulgaris and Its Active Disease Mouse Model (1) Pemphigus is a group of chronic blistering skin diseases in which autoanti- bodies are directed against…
Month: July 2021
Passive transfer of anti-laminin 5 antibodies induces subepidermal blisters in neonatal mice
Passive transfer of anti-laminin 5 antibodies induces subepidermal blisters in neonatal mice.(1) Laminin 5 (a3b3g2) is a heterotrimeric adhesion molecule that is associated with anchoring…
Collagen XVII
Collagen XVII (1) Collagen XVII is expressed in skin, oral mucosa, ocular conjunctiva, epithelial basement membrane of the cornea, upper esophagus, transitional epithelium of the…
A Multivalent Assay to Detect Glycosaminoglycan, Protein, Collagen, RNA, and DNA Content in Milligram Samples of Cartilage or Hydrogel-Based Repair Cartilage
A Multivalent Assay to Detect Glycosaminoglycan, Protein, Collagen, RNA, and DNA Content in Milligram Samples of Cartilage or Hydrogel-Based Repair Cartilage (1) Mature cartilage tissue…
Two Forms of Collagen XVII in Keratinocytes
Two Forms of Collagen XVII in Keratinocytes(1) Collagen XVII, also known as the 180-kDa bullous pemphigoid antigen or BP180, is a structural component of the…
The Shed Ectodomain of Collagen XVII/BP180 Is Targeted by Autoantibodies in Different Blistering Skin Diseases
The Shed Ectodomain of Collagen XVII/BP180 Is Targeted by Autoantibodies in Different Blistering Skin Diseases (1) Collagen XVII occurs in two forms, as a full-length…
Plasmin Plays a Role in the In Vitro Generation of the Linear IgA Dermatosis Antigen LADB97
Plasmin Plays a Role in the In Vitro Generation of the Linear IgA Dermatosis Antigen LADB97(1) In bullous pemphigoid (BP), autoantibodies target immunodominant epitopes mainly…
Immunoglobulin switch circular DNA in the mouse infected with Nippostrongylus brasiliensis: evidence for successive class switching from mu to epsilon via gamma 1
Immunoglobulin switch circular DNA in the mouse infected with Nippostrongylus brasiliensis: evidence for successive class switching from mu to epsilon via gamma 1.(1) As B…
The murine IgG1/IgE class switch program
The murine IgG1/IgE class switch program (1) In murine B cells immunoglobulin class switching to IgGl and IgE is controlled by the same cytokine, interleukin-4…