Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface (1) Antibodies to the Gram-negative bacterial surface, induced after natural…

Th17 Cells Promote Autoimmune Anti-Myeloperoxidase Glomerulonephritis(1) The primary antigenic targets of Anti-neutrophil cytoplasmic antibody (ANCA) are found abundantly in azurophilic granules of neutrophils and comprise…

Activation of Dendritic Cells through the Interleukin 1 Receptor 1 Is Critical for the Induction of Autoimmune Myocarditis (1) In the context of autoimmunity, IL-1…

Glomerulopathy Induced by Immunization with a Peptide Derived from the Goodpasture Antigen α3IV-NC1(1) The major autoantigen is the noncollagenous domain 1 of the a3-chain of…

A Nephritogenic Rat Monoclonal Antibody to Mouse Amlnopeptidase A. Induction of Massive Albuminuria after a Single Intravenous Injection. (1) The hydrolase dipeptidyl peptidase IV (DPP…

Mouse Monoclonal Antibodies with Anti-A, Anti-B and Anti-A,B Specificities; Some Superior to Human Polyclonal ABO Reagents (1) Using BALB/c mice, a finaI high-dose booster schedule…

Inhibition of Interleukin-10 Signaling Induces Microbiota-dependent Chronic Colitis in Apolipoprotein E Deficient Mice (1) Inflammatory bowel diseases (IBDs) are widely believed to be due to…

Structural and functional characterization of the Curli adaptor protein CsgF(1) Untangling a Repetitive Amyloid Sequence: Correlating Biofilm‐Derived and Segmentally Labeled Curli Fimbriae by Solid‐State NMR…

Biodegradable zinc oxide composite scaffolds promote osteochondral differentiation of mesenchymal stem cells (1) Zinc is an essential nutrient for many physiological functions including growth, DNA…

T cell epitope mimicry between Sjögren’s syndrome Antigen A (SSA)/Ro60 and oral, gut, skin and vaginal bacteria (1) Cross-reactivity between Ro60 and EBV protein EBNA-1…

Arthropathic Properties Related to the Molecular Weight of Peptidoglycan-Polysaccharide Polymers of Streptococcal Cell Walls (1) The covalently bound polymers of peptidoglycan and group-specific polysaccharide (PG-APS)…

Does age matter? The impact of rodent age on study outcomes (1) The quality of data obtained from rodent models and these factors differ according…

Optimized extraction of glycosaminoglycans from normal and osteoarthritic cartilage for glycomics profiling (1) The functioning ability of cartilage is dependent on the maintenance of the…

Anti-Neutrophil Cytoplasmic Antibodies and Effector CD4 Cells Play Nonredundant Roles in Anti-Myeloperoxidase Crescentic Glomerulonephritis(1) MPO-ANCA–associated “pauci-immune” crescentic GN in humans therefore may be a three-step…

Extraction, Isolation and Analysis of Chondroitin Sulfate Glycosaminoglycans (1) Glycosaminoglycans (GAGs) are a straight chain anionic polysaccharide composed of repeating disaccharide units of hexosamine (glucosamine…

A semi-empirical method for prediction of antigenic determinants on protein antigens(1) Identification of epitopes on proteins would be useful for diagnostic purposes and also in…

Animal models of anti-neutrophil cytoplasmic antibody-associated vasculitis(1). Anti-neutrophil cytoplasmic antibody (ANCA) vasculitis is a severe systemic disease that affects joints, lungs, kidneys, skin and other…

Experimental Autoimmune Anti-MPO Disease Induced by Active Immunization With MPO (1) GN is triggered by injection of a low dose of sheep anti-mouse glomerular basement…

Toll-like Receptor 2 Induces Th17 Myeloperoxidase Autoimmunity While Toll-like Receptor 9 Drives Th1 Autoimmunity in Murine Vasculitis (1) When T-cells are activated, CD4 cells differentiate…

A new mouse model of anti-GBM disease sheds light on maternal transfer of alloantibodies in glomerular disease (1) In Membranous nephropathy (MN), the two main…